THIS SUNDAY, APRIL 12TH AT 3PM Please join the East Central Deanery for a special prayer service in celebration of the Solemnity of Divine Mercy in connection with the Biloxi Diocese’s 50th Anniversary. This time of prayer will include exposition of the Blessed Sacrament, recitation of the Divine Mercy Chaplet, veneration of the Divine Mercy image, a reflection on Divine Mercy, and opportunities for the Sacrament of Reconciliation and prayers for healing. This event will take place here at Nativity of the Blessed Virgin Mary Cathedral at 3:00 p.m. There will be a reception following the celebration in the Sacred Heart Center, directly behind the Cathedral.

Father Godfrey and Father Bart will be on a Priest Retreat from April 13th through April 16th. THERE WILL BE NO 8:00 AM SERVICE ON MONDAY, APRIL 13TH THRU THURSDAY, 16TH.. Deacon Johnny will have morning Communion Service at 6:30 am on those dates.

Nativity B.V.M. Cathedral will hold our Vacation Bible School June 22- 26, 2026, 9:00 a.m. - 12:00 noon daily. Click here to see more details! The participant ages: Rising 1st graders - Rising 6th graders (just completed Kindergarten - 5th grade). Cost: $30 per child. Volunteers needed!!!! Rising 7th graders through Adults are welcome to join us and volunteer for 1 day or all 5 days! Get your volunteer hours!

The Marian Chapel will be open on Holy Thursday, April 2, from 11 a.m. to 1 p.m. for anyone who would like to spend some quiet time in prayer among the saints. Volunteers will open the doors and be present if you have questions about the reliquary. All are invited.

Please consider sending in your Easter Flower donations along with the names of your loved ones. We will pray for each one this Easter. We have provided Easter Flower Envelopes in the pews. You can also donate using the secure portal on our website.

Please contact the Church Rectory office if you are interested in lighting the Sanctuary Lamp for a loved one, purchasing the Altar Flowers or having a Mass said for a loved one. These are beautiful ways to remember and celebrate special people in our lives. Please consider honoring your loved ones, both living and deceased. Having a Mass said for our deceased loved ones, a loved one suffering from illness or possibly battling something in their life is a beautiful gift to give to them; more so, any individual can ask for Mass to be celebrated for special intention.

The Music & Fine Arts Ministry Program of the Nativity of the Blessed Virgin Mary Cathedral under the direction of Terry Maddox presents "Lenten Lessons and Reflections” on Sunday, March 22nd at 4:00 pm.

A Lenten penance service will be held at the Cathedral of the Nativity of the Blessed Virgin Mary on Monday, March 16th at 6 PM.

The Cathedral of the Nativity of the Blessed Virgin Mary is proud to announce that the St. Joseph Altar will be on display at the Sacred Heart Center on Thursday, March 19, 2025, St. Joseph’s Day, from 10 a.m. until 3 p.m. Lunch will be served at 12:00 p.m. (Noon).

On Saturday, March 14th, we will have a morning of prayer. beginning at 8:30 a.m. until 12:00 Noon, in the Marian Chapel. Please join us in prayer and reflection surrounded by the relics of the Saints!

Stations of the Cross will be held every Friday during Lent at 6PM in the Nativity of the Blessed Virgin Mary Cathedral! Come join us in praise!

Bishop Kihneman invites everyone to recognize 2026 as a year of the Divine Mercy Chaplet as the Diocese of Biloxi celebrates it's 50th Anniversary. Pray the Divine Mercy Chaplet online, or click here to download a copy at the USCCB site.

The Diocesan Walk for Life and Rosary Rally will be held on SUNDAY, JANUARY 25TH at Nativity BVM (870 Howard Ave, Biloxi, MS 39530) in Biloxi. The event will begin at 2pm. Our day will consist of with praying the Rosary, Mass Celebrated by Bishop Kinehman, March for Life (walk), music, guest speakers (including the Bishop), and Adoration. For more information, please see the bulletin or click here to contact the Diocesan Pro Life Office.

Nativity BVM Cathedral's Vocations Ministry Team invites you to celebrate our priests and "taco 'bout" vocations! "Lettuce" pray together at this fun family friendly event with food and fellowship, united in Faith and Community! WHEN: SUNDAY, JANUARY 18, 2026 FOLLOWING THE 11AM MASS WHERE: INSIDE THE SACRED HEART CENTER LOCATED JUST BEHIND THE CATHEDRAL

Please click to see full details on our Music Ministry Offerings! All three of our Choirs come back from holiday the week of January 11th!

Please see the link for Mass Times for Christmas and New Years

There will be a meeting for Confirmandi (Juniors/Seniors that are requesting the Sacrament of Confirmation in the Spring of 2026) and Parent(s)/Guardian(s) on Sunday, January 4, at 6:40 pm at Nativity BVM Cathedral’s Sacred Heart Center in the Youth Ministry room.

"Gloria in Excelsis" and "Mobile Vocal Arts" Choral Societies present their Annual Holiday Concert, Sunday, December 21st at 4 PM at the Nativity of the Blessed Virgin Mary Cathedral in Downtown Biloxi. The program is free and open to the public.

Nativity BVM Elementary School's Cherub and Children's Choir will offer their annual Children's Choir Christmas Concert in the School Gymnatorium on December 10th @ 9:00 A.M. and 5:30 P.M. For more information, please contact the School Office at 228-432-2269.

On Saturday, December 13th, 2025 we will have an Advent Day of Prayer and Reflections, beginning after the 8:00 a.m. Mass in the Marion Chapel. All are invited to join us in prayer amongst the relics of the Saints.